Node

NCBI Gene

Symbol ager Gene ID 177
IF 1.8% Link Number 1
Full Name advanced glycosylation end product-specific receptor
Aliases RAGE
Summary

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

Node Expression

# PMID Condition Expression Material  
1 27044590 group(MSC AD14day) (0 -1.60944715684443) hMSC

Relation Chart

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Relation Table (1 record)

# Source IF(%) Relation Target IF(%) Type Method PMID
1 ager 1.8 activates tp53 29.1 bind to protein   23150674

Prediction Chart

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Prediction Table (7 records)

# Source IF(%) Target IF(%) Species Agreement Computational Predictions / PMID
1 mirn134 2.9 ager 1.8 Mouse -0.10 3
2 mirn185 22.6 ager 1.8 Human 0.43 3
3 mirn201 1.8 ager 1.8 Mouse -0.08 3
4 mirn201 1.8 ager 1.8 Mouse -0.08 3
5 nfkb1 41.4 ager 1.8 Human 100.00 18622638
6 pparg 77.1 ager 1.8 Human 100.00 18855759
7 rela 34.9 ager 1.8 Human 100.00 18622638