Node
NCBI Gene
| Symbol | cold | Gene ID | |
| IF | 2% | Link Number | 8 |
| Full Name | cold exposure | ||
| Aliases | cold exposure | ||
| Summary | |||
Node Summary
PMID: 21723505
Interestingly, SMAD3‑null mice also display increases in the levels of BAT-specific markers in WAT compartments when kept on a regular diet,suggesting that this pathway may be involved in the transdifferentiation of WAT to BAT on cold exposure.
Relation Chart
Chart Legend
Relation Table (8 records)
| # | Source | IF(%) | Relation | Target | IF(%) | Type | Method | PMID |
|---|---|---|---|---|---|---|---|---|
| 1 | cold | 2 | activates | sirt3 | 3.2 | others | Northern blot,Overexpression and knockdown | 15653680 |
| 2 | cold | 2 | inhibits | mef2c | 6.2 | others | 23143398 | |
| 3 | cold | 2 | inhibits | mirn133 | 4 | others | 23143398 | |
| 4 | cold | 2 | inhibits | mirn27a | 16.9 | others | Bioinformatic,Cell culture and differentiation,Lipolysis assay,Northern blot,Overexpression and knockdown,Western blot | 24238035 |
| 5 | cold | 2 | inhibits | mirn27b | 10.4 | others | Bioinformatic,Cell culture and differentiation,Lipolysis assay,Northern blot,Overexpression and knockdown,Western blot | 24238035 |
| 6 | cold | 2 | inhibits | prb | 3.8 | phosphorylation | (IHC) immunohistochemistry,Cell culture and differentiation,Overexpression and knockdown,RT-qPCR or RT-PCR,Western blot | 15024128 |
| 7 | cold | 2 | inhibits | odc1 | 5.4 | alternative splicing | 19825180 | |
| 8 | cold | 2 | activates | mirn455 | 8.2 | others | RT-qPCR or RT-PCR | 26303948 |
Prediction Chart
Chart Legend
Prediction Table (0 record)
| # | Source | IF(%) | Target | IF(%) | Species | Agreement | Computational Predictions / PMID |
|---|---|---|---|---|---|---|---|
Sorry, no matching records found. |
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