Node

NCBI Gene

Symbol mirn98 Gene ID  
IF 20.1% Link Number 3
Full Name MI0000100
Aliases miR-98,hsa-mir-98,bta-mir-98
Summary

The Let-7 microRNA precursor was identified from a study of developmental timing in C. elegans, and was later shown to be part of a much larger class of non-coding RNAs termed microRNAs. miR-98 microRNA precursor from human is a let-7 family member. Let-7 miRNAs have now been predicted or experimentally confirmed in a wide range of species (MIPF0000002). miRNAs are initially transcribed in long transcripts (up to several hundred nucleotides) called primary miRNAs (pri-miRNAs), which are processed in the nucleus by Drosha and Pasha to hairpin structures of about ~70 nucleotide. These precursors (pre-miRNAs) are exported to the cytoplasm by exportin5, where they are subsequently processed by the enzyme Dicer to a ~22 nucleotide mature miRNA. The involvement of Dicer in miRNA processing demonstrates a relationship with the phenomenon of RNA interference.

Node Expression

# PMID Condition Expression Material  
1 16870994 pre-adipocyte differentiation Up   3T3-L1
2 21135128 preadipocytes VS adipocytes (1 2) (1 0.065) preadipocyte
3 20423511 high VS low fat group(1 2) fold(1.58 1) IMF
4 20126310 dif(0 7 14) (1 0.6 1) preadipocyte
5 20126310 Obese vs. Lean(1 2) 1 -1.23 preadipocyte

Relation Chart

Chart Legend

Relation Table (3 records)

 
# Source IF(%) Relation Target IF(%) Type Method PMID
1 hypoxia 2 inhibits mirn98 20.1 others Review 26098770
2 mirn98 20.1 inhibits edn1 8.4 bind to RNA Gene knockout,Overexpression and knockdown,Reporter 26098770
3 pparg 77.1 activates mirn98 20.1 bind to DNA Gene knockout,Overexpression and knockdown,Reporter 26098770

Prediction Chart

Chart Legend

Prediction Table (123 records)

 
# Source IF(%) Target IF(%) Species Agreement Computational Predictions / PMID
1 mirn98 20.1 ahr 6.7 Human 100.00 1
2 mirn98 20.1 cbx5 4.7 Human 100.00 1
3 mirn98 20.1 ccnf 3.3 Human 100.00 1
4 mirn98 20.1 cdkn1a 16.2 Human 100.00 1
5 mirn98 20.1 cdkn1b 7.6 Human 100.00 1
6 mirn98 20.1 cdkn2b 7.5 Human 100.00 1
7 mirn98 20.1 ecm2 2.2 Human 100.00 1
8 mirn98 20.1 fas 10.3 Human 100.00 1
9 mirn98 20.1 fndc3b 4 Human 100.00 1
10 mirn98 20.1 hmga2 14 Human 100.00 1
11 mirn98 20.1 irs2 14.9 Human 100.00 1
12 mirn98 20.1 ppargc1a 16.3 Human 100.00 1
13 mirn98 20.1 suv39h1 4.9 Human 100.00 1
14 mirn98 20.1 tgfbr1 9 Human 100.00 1
15 mirn98 20.1 tp53 29.1 Human 100.00 1
16 mirn98 20.1 ahr 6.7 Human 100.00 1
17 mirn98 20.1 ccna2 5.6 Human 100.00 1
18 mirn98 20.1 cdkn1b 7.6 Human 100.00 1
19 mirn98 20.1 fndc3b 4 Human 100.00 1
20 mirn98 20.1 heg1 4.3 Human 100.00 1
21 mirn98 20.1 hk2 9.5 Human 100.00 1
22 mirn98 20.1 hmga2 14 Human 100.00 2
23 mirn98 20.1 ifnar1 2.4 Human 100.00 1
24 mirn98 20.1 irs2 14.9 Human 100.00 1
25 mirn98 20.1 klf3 5.2 Human 100.00 1
26 mirn98 20.1 spry1 5.3 Human 100.00 1
27 mirn98 20.1 tgfbr1 9 Human 100.00 1
28 mirn98 20.1 osmr 6.5 Human 100.00 1
29 mirn98 20.1 rps6kb1 5.9 Human 100.00 1
30 mirn98 20.1 rgs16 4.3 Human 100.00 1
31 mirn98 20.1 schip1 3 Human 100.00 1
32 mirn98 20.1 sema3c 3.9 Human 100.00 1
33 mirn98 20.1 s100a8 2.5 Human 100.00 1
34 mirn98 20.1 schip1 3 Human 100.00 1
35 mirn98 20.1 slc20a1 5.2 Human 100.00 1
36 mirn98 20.1 slc5a6 5.2 Human 100.00 1
37 mirn98 20.1 slc7a6 3.9 Human 100.00 1
38 mirn98 20.1 spry1 5.3 Human 100.00 1
39 mirn98 20.1 suv39h1 4.9 Human 100.00 1
40 mirn98 20.1 tcerg1 5.6 Human 196.00 1
41 mirn98 20.1 tead1 2.9 Human 197.00 1
42 mirn98 20.1 tfpi 4.4 Human 198.00 1
43 mirn98 20.1 tgfbr1 9 Human 199.00 1
44 mirn98 20.1 thbs1 11.5 Human 200.00 1
45 mirn98 20.1 tead1 2.9 Human 201.00 1
46 mirn98 20.1 tgfbr1 9 Human 202.00 1
47 mirn98 20.1 thbs1 11.5 Human 203.00 1
48 mirn98 20.1 tnfrsf21 6.5 Human 282.00 1
49 mirn98 20.1 tnfsf9 2.7 Human 283.00 1
50 mirn98 20.1 tp53 29.1 Human 100.00 1
51 mirn98 20.1 tram2 2 Human 345.00 1
52 mirn98 20.1 txlng 4.2 Human 100.00 1
53 mirn98 20.1 wars2 1 Human 100.00 1
54 mirn98 20.1 znf200 3.1 Human 100.00 1
55 mirn98 20.1 ifnar1 2.4 Human 100.00 1
56 mirn98 20.1 sox9 9.6 Mouse -0.21 3
57 mirn98 20.1 ezh2 11.5 Mouse 100.00 1
58 mirn98 20.1 cdc34 2.5 Mouse -0.02 3
59 mirn98 20.1 trim63 1.7 Mouse 1.29 3
60 mirn98 20.1 ahr 6.7 Human 100.00 1
61 mirn98 20.1 cbx5 4.7 Human 100.00 1
62 mirn98 20.1 ccna2 5.6 Human 100.00 1
63 mirn98 20.1 ccnf 3.3 Human 100.00 1
64 mirn98 20.1 cdkn1a 16.2 Human 100.00 1
65 mirn98 20.1 cdkn1b 7.6 Human 100.00 1
66 mirn98 20.1 cdkn2b 7.5 Human 100.00 1
67 mirn98 20.1 ecm2 2.2 Human 100.00 1
68 mirn98 20.1 ezh2 11.5 Human 100.00 2
69 mirn98 20.1 fas 10.3 Human 100.00 1
70 mirn98 20.1 fndc3b 4 Human 100.00 1
71 mirn98 20.1 heg1 4.3 Human 100.00 1
72 mirn98 20.1 hk2 9.5 Human 100.00 1
73 mirn98 20.1 hmga2 14 Human 100.00 2
74 mirn98 20.1 ifnar1 2.4 Human 100.00 1
75 mirn98 20.1 irs2 14.9 Human 100.00 1
76 mirn98 20.1 klf3 5.2 Human 100.00 1
77 mirn98 20.1 mtus1 2.5 Human 100.00 1
78 mirn98 20.1 myc 32.8 Human 100.00 1
79 mirn98 20.1 osmr 6.5 Human 100.00 1
80 mirn98 20.1 pmaip1 4.2 Human 100.00 1
81 mirn98 20.1 pmaip1 4.2 Human 100.00 1
82 mirn98 20.1 pou2f1 4.8 Human 100.00 1
83 mirn98 20.1 rgs16 4.3 Human 100.00 1
84 mirn98 20.1 rps6kb1 5.9 Human 100.00 1
85 mirn98 20.1 s100a8 2.5 Human 100.00 1
86 mirn98 20.1 schip1 3 Human 100.00 1
87 mirn98 20.1 sema3c 3.9 Human 100.00 1
88 mirn98 20.1 slc20a1 5.2 Human 100.00 1
89 mirn98 20.1 slc5a6 5.2 Human 100.00 1
90 mirn98 20.1 slc7a6 3.9 Human 100.00 1
91 mirn98 20.1 sox9 9.6 Human -0.21 3
92 mirn98 20.1 spry1 5.3 Human 100.00 1
93 mirn98 20.1 suv39h1 4.9 Human 100.00 1
94 mirn98 20.1 tcerg1 5.6 Human 100.00 1
95 mirn98 20.1 tead1 2.9 Human 100.00 1
96 mirn98 20.1 tfpi 4.4 Human 100.00 1
97 mirn98 20.1 tgfbr1 9 Human 100.00 1
98 mirn98 20.1 thbs1 11.5 Human 100.00 1
99 mirn98 20.1 tnfrsf21 6.5 Human 100.00 1
100 mirn98 20.1 tnfsf9 2.7 Human 100.00 1
101 mirn98 20.1 tp53 29.1 Human 100.00 1
102 mirn98 20.1 tram2 2 Human 100.00 1
103 mirn98 20.1 txlng 4.2 Human 100.00 1
104 mirn98 20.1 wars2 1 Human 100.00 1
105 mirn98 20.1 znf200 3.1 Human 100.00 1
106 mirn98 20.1 cyp19a1 4.7 Human 100.00 1
107 mirn98 20.1 hbegf 3.6 Human 100.00 1
108 mirn98 20.1 mitf 6.1 Human 100.00 1
109 mirn98 20.1 cdc25a 3 Human 100.00 1
110 mirn98 20.1 hbegf 3.6 Human 100.00 1
111 mirn98 20.1 mitf 6.1 Human 100.00 1
112 mirn98 20.1 serp1 1.2 Human 100.00 1
113 mirn98 20.1 pitx2 5.4 Mouse -0.76 3
114 mirn98 20.1 nr2f6 2.9 Human 100.00 1
115 mirn98 20.1 adamts5 2.6 Human 100.00 1
116 mirn98 20.1 tnfsf10 4.4 Human 100.00 1
117 mirn98 20.1 nolc1 3.1 Human 100.00 1
118 mirn98 20.1 ror1 2.6 Human 100.00 1
119 mirn98 20.1 adamts5 2.6 Human 100.00 1
120 mirn98 20.1 adamts5 2.6 Human 100.00 1
121 mirn98 20.1 jag1 5.8 Human 100.00 1
122 mirn98 20.1 jag1 5.8 Human 100.00 1
123 mirn98 20.1 tagln 3 Human   3