NCBI Gene
| Symbol | noct | Gene ID | 25819 |
| IF | 0.9% | Link Number | 1 |
| Full Name | nocturnin | ||
| Aliases | CCR4L,CCRN4L,Ccr4c,NOC | ||
| Summary | The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008] |
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Node Summary
PMID: 20498072
Nocturnin is a circadian rhythm-regulated protein that is required for adipogenesis by acting as a coactivator for PPARγ and enhancing its activity during terminal differentiation.
PMID: 20498072
Nocturnin is a circadian rhythm-regulated protein that is required for adipogenesis by acting as a coactivator for PPARγ and enhancing its activity during terminal differentiation.
Node Expression
| # | PMID | Condition | Expression | Material | |
|---|---|---|---|---|---|
| 1 | 15051823 | DME,dif 12days+TZD(0 24)h | Up(1 2.3)fold | 3T3-L1 |
Relation Chart
Chart Legend
Relation Table (1 record)
| # | Source | IF(%) | Relation | Target | IF(%) | Type | Method | PMID |
|---|---|---|---|---|---|---|---|---|
| 1 | noct | 0.9 | activates | pparg | 77.1 | others | (IP)immunoprecipitation,Reporter,Western blot | 20498072 |
Prediction Chart
Chart Legend
Prediction Table (0 record)
| # | Source | IF(%) | Target | IF(%) | Species | Agreement | Computational Predictions / PMID |
|---|---|---|---|---|---|---|---|
Sorry, no matching records found. |
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