Node

NCBI Gene

Symbol noct Gene ID 25819
IF 0.9% Link Number 1
Full Name nocturnin
Aliases CCR4L,CCRN4L,Ccr4c,NOC
Summary

The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]

Node Summary

PMID: 20498072

Nocturnin is a circadian rhythm-regulated protein that is required for adipogenesis by acting as a coactivator for PPARγ and enhancing its activity during terminal differentiation.

PMID: 20498072

Nocturnin is a circadian rhythm-regulated protein that is required for adipogenesis by acting as a coactivator for PPARγ and enhancing its activity during terminal differentiation.

Node Expression

# PMID Condition Expression Material  
1 15051823 DME,dif 12days+TZD(0 24)h Up(1 2.3)fold 3T3-L1

Relation Chart

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Relation Table (1 record)

# Source IF(%) Relation Target IF(%) Type Method PMID
1 noct 0.9 activates pparg 77.1 others (IP)immunoprecipitation,Reporter,Western blot 20498072

Prediction Chart

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Prediction Table (0 record)

# Source IF(%) Target IF(%) Species Agreement Computational Predictions / PMID
Sorry, no matching records found.