Node
NCBI Gene
| Symbol | nr4a1 | Gene ID | 3164 |
| IF | 8.1% | Link Number | 0 |
| Full Name | nuclear receptor subfamily 4, group A, member 1 | ||
| Aliases | GFRP1,HMR,N10,NAK-1,NGFIB,NP10,NUR77,TR3 | ||
| Summary | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
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Node Expression
| # | PMID | Condition | Expression | Material | |
|---|---|---|---|---|---|
| 1 | 26111340 | hMSC uncommitted High expression | Up-Regulated | MSC | |
| 2 | 26505482 | low VS high IMF group (1 2) | (1 3.36) | IMF | |
| 3 | 26505482 | low VS high IMF group (1 2) | (1 3.362788647) | IMF | |
| 4 | 23967297 | adi 6M std VS ob/ob (1 2) | HFD-ob/obEadi(1 -11.7) | mouse | |
| 5 | 23967297 | E-adi(6 14 52)M | lipolysis-age(1 -4.03 -4.62) | mouse | |
| 6 | 23967297 | B-adi(6 14 18) | lipolysis-age(1 2.53 1.11) | mouse | |
| 7 | 12137940 | 0 2 8 16 24 | 1 6 3 2 2 | 3T3-L1 | |
| 8 | 11445576 | adipo-enriched | 3T3-L1 | ||
| 9 | 11445576 | dif(-1 0 0.25 0.5 1 2 3 4 7 28) | dif(1 5 10 10 10 8 8 6 3 1) | 3T3-L1 |
Relation Chart
Chart Legend
Relation Table (0 record)
| # | Source | IF(%) | Relation | Target | IF(%) | Type | Method | PMID |
|---|---|---|---|---|---|---|---|---|
Sorry, no matching records found. |
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Prediction Chart
Chart Legend
Prediction Table (17 records)
| # | Source | IF(%) | Target | IF(%) | Species | Agreement | Computational Predictions / PMID |
|---|---|---|---|---|---|---|---|
| 1 | hif1a | 21.7 | nr4a1 | 8.1 | Human | 100.00 | 14729605 |
| 2 | mef2c | 6.2 | nr4a1 | 8.1 | Human | 100.00 | 18079734 |
| 3 | nr4a1 | 8.1 | e2f1 | 22.1 | Human | 100.00 | 12947120 |
| 4 | nr4a1 | 8.1 | ccna2 | 5.6 | Human | 100.00 | 12842839 |
| 5 | nr4a1 | 8.1 | cdkn1b | 7.6 | Human | 100.00 | 12842839 |
| 6 | nr4a1 | 8.1 | cyp11a1 | 3 | Human | 100.00 | 20083153 |
| 7 | nr4a1 | 8.1 | faslg | 3 | Human | 100.00 | 14563113 |
| 8 | nr4a1 | 8.1 | mdm2 | 4.2 | Human | 100.00 | 17139261 |
| 9 | nr4a1 | 8.1 | mmp2 | 15.9 | Human | 100.00 | 22551568 |
| 10 | nr4a1 | 8.1 | serpine1 | 15.7 | Human | 100.00 | 12506026 |
| 11 | nr4a1 | 8.1 | star | 5 | Human | 100.00 | 20083153 |
| 12 | nr4a1 | 8.1 | timp2 | 8.5 | Human | 100.00 | 22551568 |
| 13 | nr4a1 | 8.1 | tnf | 18.8 | Human | 100.00 | 19213954 |
| 14 | nr4a1 | 8.1 | cyp17a1 | 3 | Human | 100.00 | 20083153 |
| 15 | nr4a1 | 8.1 | hsd3b2 | 2.1 | Human | 100.00 | 15666793 |
| 16 | rela | 34.9 | nr4a1 | 8.1 | Human | 100.00 | 15024051 |
| 17 | sp1 | 40.7 | nr4a1 | 8.1 | Human | 100.00 | 8961265 |

