Node

NCBI Gene

Symbol nr4a1 Gene ID 3164
IF 8.1% Link Number 0
Full Name nuclear receptor subfamily 4, group A, member 1
Aliases GFRP1,HMR,N10,NAK-1,NGFIB,NP10,NUR77,TR3
Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Node Expression

# PMID Condition Expression Material  
1 26111340 hMSC uncommitted High expression Up-Regulated MSC
2 26505482 low VS high IMF group (1 2) (1 3.36) IMF
3 26505482 low VS high IMF group (1 2) (1 3.362788647) IMF
4 23967297 adi 6M std VS ob/ob (1 2) HFD-ob/obEadi(1 -11.7) mouse
5 23967297 E-adi(6 14 52)M lipolysis-age(1 -4.03 -4.62) mouse
6 23967297 B-adi(6 14 18) lipolysis-age(1 2.53 1.11) mouse
7 12137940 0 2 8 16 24 1 6 3 2 2 3T3-L1
8 11445576   adipo-enriched 3T3-L1
9 11445576 dif(-1 0 0.25 0.5 1 2 3 4 7 28) dif(1 5 10 10 10 8 8 6 3 1) 3T3-L1

Relation Chart

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Relation Table (0 record)

# Source IF(%) Relation Target IF(%) Type Method PMID
Sorry, no matching records found.

Prediction Chart

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Prediction Table (17 records)

# Source IF(%) Target IF(%) Species Agreement Computational Predictions / PMID
1 hif1a 21.7 nr4a1 8.1 Human 100.00 14729605
2 mef2c 6.2 nr4a1 8.1 Human 100.00 18079734
3 nr4a1 8.1 e2f1 22.1 Human 100.00 12947120
4 nr4a1 8.1 ccna2 5.6 Human 100.00 12842839
5 nr4a1 8.1 cdkn1b 7.6 Human 100.00 12842839
6 nr4a1 8.1 cyp11a1 3 Human 100.00 20083153
7 nr4a1 8.1 faslg 3 Human 100.00 14563113
8 nr4a1 8.1 mdm2 4.2 Human 100.00 17139261
9 nr4a1 8.1 mmp2 15.9 Human 100.00 22551568
10 nr4a1 8.1 serpine1 15.7 Human 100.00 12506026
11 nr4a1 8.1 star 5 Human 100.00 20083153
12 nr4a1 8.1 timp2 8.5 Human 100.00 22551568
13 nr4a1 8.1 tnf 18.8 Human 100.00 19213954
14 nr4a1 8.1 cyp17a1 3 Human 100.00 20083153
15 nr4a1 8.1 hsd3b2 2.1 Human 100.00 15666793
16 rela 34.9 nr4a1 8.1 Human 100.00 15024051
17 sp1 40.7 nr4a1 8.1 Human 100.00 8961265