Node

NCBI Gene

Symbol paxip1 Gene ID 22976
IF 2.1% Link Number 2
Full Name PAX interacting (with transcription-activation domain) protein 1
Aliases CAGF28,CAGF29,PACIP1L,PTIP,TNRC2,PAXIP1
Summary

This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. [provided by RefSeq, Jul 2008]

Node Summary

PMID: 19583951

by controlling the induction of PPARγ and C/EBPα, the two principal adipogenic transcriptional factors, histone methylation regulator PTIP plays a critical role in adipogenesis.

Node Expression

# PMID Condition Expression Material  
1 27108396 Control VS hADSC day 1 post-adipogenic induction (1 -1.24) hADSC
2 27044590 group(MSC AD14day) (0 -1.41869081863014) hMSC

Relation Chart

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Relation Table (2 records)

# Source IF(%) Relation Target IF(%) Type Method PMID
1 paxip1 2.1 activates cebpa 40.7 epgenetic modification Cell culture and differentiation,ChIP,Microarray,Northern blot,RT-qPCR or RT-PCR,Western blot 19583951
2 paxip1 2.1 activates pparg 77.1 epgenetic modification Cell culture and differentiation,ChIP,Microarray,Northern blot,RT-qPCR or RT-PCR,Western blot 19583951

Prediction Chart

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Prediction Table (2 records)

# Source IF(%) Target IF(%) Species Agreement Computational Predictions / PMID
1 mirn32 5.8 paxip1 2.1 Human 100.00 2
2 mirn32 5.8 paxip1 2.1 Human 100.00 2