Node
NCBI Gene
| Symbol | paxip1 | Gene ID | 22976 |
| IF | 2.1% | Link Number | 2 |
| Full Name | PAX interacting (with transcription-activation domain) protein 1 | ||
| Aliases | CAGF28,CAGF29,PACIP1L,PTIP,TNRC2,PAXIP1 | ||
| Summary | This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. [provided by RefSeq, Jul 2008] |
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Node Summary
PMID: 19583951
by controlling the induction of PPARγ and C/EBPα, the two principal adipogenic transcriptional factors, histone methylation regulator PTIP plays a critical role in adipogenesis.
Node Expression
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Relation Table (2 records)
| # | Source | IF(%) | Relation | Target | IF(%) | Type | Method | PMID |
|---|---|---|---|---|---|---|---|---|
| 1 | paxip1 | 2.1 | activates | cebpa | 40.7 | epgenetic modification | Cell culture and differentiation,ChIP,Microarray,Northern blot,RT-qPCR or RT-PCR,Western blot | 19583951 |
| 2 | paxip1 | 2.1 | activates | pparg | 77.1 | epgenetic modification | Cell culture and differentiation,ChIP,Microarray,Northern blot,RT-qPCR or RT-PCR,Western blot | 19583951 |
Prediction Chart
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